Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

303open jobs
$108k–$175ktypical salary
147companies hiring
2added this week
93%remote

Open Python roles

66 jobs

Senior Risk Analyst

Coinbase · Remote
Direct applyrisk managementdata analysisSQLPython
$167k–$197k 6 days ago View →

Senior Onchain Investigator

Coinbase · Remote
Direct applyPythonGoSQL
$52k–$88k 26 days ago View →

Threat Intelligence Platform Engineer

Coinbase · Remote
Direct applyPythonGoStorm
$82k–$138k 1 month ago View →

Staff Frontend Engineer / Senior Backend Engineer

Douro Labs / Zerion · Remote
Direct applyTypeScriptReactGoDocker
$120k–$200k 1 month ago View →

Threat Intelligence Platform Engineer

Coinbase · Remote
Direct applyPythonGoStorm
$145k–$170k 1 month ago View →

Member of Trading Operations

Anchorage · Remote
Direct applycryptocurrenciesblockchain technologyfinancial operationsrisk management
$45k–$75k 1 month ago View →

Senior Staff Software Engineer, Finhub

Coinbase · Remote
Direct applysoftware engineeringbackend developmentdistributed systemspayments
$260k–$260k 1 month ago View →

Off-Cycle Fall 2026 Cybersecurity Internship

Galaxy Digital · Remote
Direct applyPythonRustC++Solidity
$114k–$114k 1 month ago View →

Senior Data Scientist

Coinbase · Remote
Direct applySQLPythondata visualizationETL
$133k–$140k 1 month ago View →

Senior Backend Engineer / Senior QA Engineer / SDET

Zerion / Trust Wallet · Remote
Direct applyGoDockerK8sPostgreSQL
$80k–$160k 1 month ago View →

Core Developer - Node / Senior Site Reliability Engineer

Parity / SSV Labs · Remote
Direct applyRustSubstratenetworkingpeer-to-peer
$100k–$160k 1 month ago View →

Core Blockchain Engineer / Infrastructure / Systems Operations Engineer

Conduit / ZIGChain · Remote
Direct applyGoPythonRustPostgres
$40k–$160k 1 month ago View →

Senior AI Engineer

Dvtrading · Remote
Direct applyPythonKubernetesCI/CD
$200k–$300k 3 months ago View →

Lead, Advanced Analytics, Fraud and Safety Operations

Airbnb · Remote
Direct applydata analyticsSQLPythonR
$164k–$191k 3 months ago View →

Data Scientist, Finance

Figma · Remote
Direct applySQLPythondata modelingdata analysis
$140k–$348k 3 months ago View →

OTC Trader

Anchorage · Remote
Direct applytradingcryptoPython
$135k–$225k 3 months ago View →

Analytics Engineer

Coinbase · Remote
Direct applySQLPythondbtSnowflake
$90k–$150k 3 months ago View →

Staff Development Experience Engineer

Galaxydigitalservices · Remote
Direct applyAWSCI/CDKubernetesGitHub
$112k–$188k 3 months ago View →

Senior Developer Experience Engineer

Galaxydigitalservices · Remote
Direct applyPythonBashGoAWS
$98k–$162k 3 months ago View →

Machine Learning Engineer

Coinbase · Remote
Direct applymachine learningpythonAIdeep learning
$120k–$200k 3 months ago View →

Scientific Data Engineer

Quantori · Remote
Direct applyPythonRSQLAWS services
$81k–$138k 3 months ago View →

Experienced Quantitative Trader

Kronosresearch · Remote
Direct applyquantitative researchrisk managementstatistical analysisPython
$105k–$112k 3 months ago View →

Risk Manager (Crypto Fund / DeFi & Quant Strategies)

EMCD · Remote
Direct applyrisk managementcryptoDeFiquantitative analysis
$92k–$155k 3 months ago View →

Senior Machine Learning Engineer, CX Intelligence

Coinbase · Remote
Direct applyPythonMachine LearningAINLP
$135k–$225k 3 months ago View →

Privacy Analyst

Coinbase · Remote
Direct applySQLPythondata analysisPostgres
$60k–$100k 3 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.