Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

303open jobs
$108k–$175ktypical salary
147companies hiring
2added this week
93%remote

Open Python roles

303 jobs

DeFi Operations Specialist - Bullish

New
Bullish · Remote
DeFifinancial operationstrading supporttreasury management
$100k–$145k today View →

Senior Risk Analyst

Coinbase · Remote
Direct applyrisk managementdata analysisSQLPython
$167k–$197k 6 days ago View →

Systematic Trader

Crypto · Hybrid
Python ProgrammingSQLQuantitative TradingQuantitative Data Analysis
$38k–$62k 7 days ago View →

Trading Support Analyst

Crypto · Hybrid
Order lifecycleTroubleshootingAlgorithmic tradingExchange APIs
$75k–$125k 8 days ago View →

Trading Support Analyst

Crypto · Hybrid
PythonSQL
$75k–$125k 8 days ago View →

Systematic Trader

Crypto · Hybrid
Python ProgrammingC++SQLQuantitative Data-analysis
$38k–$62k 8 days ago View →

Senior Data Scientist / Analyst, Finance

Polymarket · Remote
Financial AnalysisAccounting FundamentalsCausal InferenceR
$200k–$300k 15 days ago View →

Software Engineer - Solutions

Alchemy · Hybrid
PythonTypeScriptAPIsSmart Contract Automation
$150k–$225k 19 days ago View →

Senior DevOps Engineer (Trading Platform)

Crypto.com · Hybrid
JavaPythonReactAg-Grid
$98k–$162k 22 days ago View →

Senior Onchain Investigator

Coinbase · Remote
Direct applyPythonGoSQL
$52k–$88k 26 days ago View →

Principal Security Architect (On-Chain & Digital Assets)

Btse · Remote
HSMMPCAWSKubernetes
$128k–$212k 26 days ago View →

Staff Platform Security Engineer

Phantom · Remote
AWSKubernetesTerraformPulumi
$200k–$250k 27 days ago View →

Team Lead Engineer - Crypto

Alpaca · Remote
PythonGoLangC/C++NodeJS
$75k–$125k 28 days ago View →

Binance Acceleration Program - Product Data Analyst

Binance · Remote
SQLPythonRData Visualization
$90k–$150k 29 days ago View →

People Intelligence Architect

Block · Remote
data engineeringdata sciencepeople analyticsagentic AI
$108k–$203k 29 days ago View →

Risk Manager, CDNA (Risk and Operations, Asia)

Crypto.com · Hybrid
PythonSQL
$112k–$188k 1 month ago View →

Threat Intelligence Platform Engineer

Coinbase · Remote
Direct applyPythonGoStorm
$82k–$138k 1 month ago View →

Finance Systems Manager

Binance · Remote
ERP SystemsPythonSQLExcel
$98k–$162k 1 month ago View →

Staff Frontend Engineer / Senior Backend Engineer

Douro Labs / Zerion · Remote
Direct applyTypeScriptReactGoDocker
$120k–$200k 1 month ago View →

Threat Intelligence Platform Engineer

Coinbase · Remote
Direct applyPythonGoStorm
$145k–$170k 1 month ago View →

Risk Manager, Quantitative

Crypto.com · Remote
PythonSQLrisk managementquantitative analysis
$105k–$175k 1 month ago View →

Risk Manager (Risk and Operations)

Crypto.com · Hybrid
PythonSQL
$45k–$75k 1 month ago View →

Member of Trading Operations

Anchorage · Remote
Direct applycryptocurrenciesblockchain technologyfinancial operationsrisk management
$45k–$75k 1 month ago View →

Lead, Technical Compliance

Gemini · Remote
PythonSQLDatabricksPyspark
$140k–$200k 1 month ago View →

Senior Staff Software Engineer, Finhub

Coinbase · Remote
Direct applysoftware engineeringbackend developmentdistributed systemspayments
$260k–$260k 1 month ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.