Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

253open jobs
$110k–$180ktypical salary
128companies hiring
9added this week
100%remote

Open Python roles

253 jobs

Senior Data Scientist

New
Veeva Systems · Remote
PythonML librariesNLP toolsBig data processing
$115k–$196k 1 day ago View →

Senior/Lead OSDU DevOps

New
Luxoft · Remote
GitLab CI/CDJavaPythonNodeJS
$150k–$242k 1 day ago View →

Senior Manager, Data Science

Chess.com · Remote
PythonSQLBigQueryGCP
$115k–$196k 2 days ago View →

Security Engineer (Python)

Binance · Remote
PythonCloud securityCI/CDKubernetes
$98k–$162k 3 days ago View →

Senior Developer Experience Engineer / Principal Mobile Engineer

Galaxy / Consensys · Remote
PythonBashGoAWS
$140k–$272k 3 days ago View →

Senior Site Reliability Engineer

Manychat · Remote
LinuxAWSKubernetesTerraform
$88k–$130k 4 days ago View →

AI Engineer (m/f/d)

BIT Capital · Remote
PythonSQLAWSDatabricks
$65k–$95k 6 days ago View →

AI Infra Engineer

Serotonin · Remote
PythonRESTGraphQLSQL
$105k–$175k 6 days ago View →

OTC Trader

Anchorage · Remote
tradingcryptoPython
$135k–$225k 6 days ago View →

Infrastructure Engineer

Gauntlet · Remote
PythonGoTypeScriptRust
$82k–$138k 7 days ago View →

Analytics Engineer

Coinbase · Remote
SQLPythondbtSnowflake
$90k–$150k 7 days ago View →

Senior Security Engineer

Gauntlet · Remote
PythonTypeScriptJavaScriptAI
$180k–$210k 7 days ago View →

Infrastructure Engineer - Gauntlet

Gauntlet · Remote
GCPKubernetesTerraformGitHub Actions
$150k–$175k 7 days ago View →

Staff Python Engineer, Document App Track

PandaDoc · Remote
PythonDjangoPostgreSQLRedis
$115k–$196k 8 days ago View →

Graduate Software Engineer

Bending Spoons · Remote
AIPythonRustgRPC
$30k–$47k 8 days ago View →

Credit Risk Analyst

Gauntlet · Remote
credit riskstructured financeasset-backed lendingPython
$160k–$195k 8 days ago View →

Platform Engineer - (Site Reliability Engineering)

Bitso · Remote
KubernetesCI/CDDevOpsPython
$112k–$188k 8 days ago View →

Application Support Engineer

Crypto.com · Remote
LinuxBashPythonSQL
$70k–$110k 8 days ago View →

Exchange Operations Automation Engineer

Crypto.com · Remote
PythonAirflowREST APILinux
$100k–$130k 8 days ago View →

Senior Agentic AI Engineer

Eigen Labs · Remote
GoPythonRustTypeScript
$187k–$253k 9 days ago View →

Data Engineer

Wynd Labs · Remote
SQLRedshiftSnowflakeApache Airflow
$100k–$140k 9 days ago View →

Technical Chief of Staff

Wynd Labs · Remote
Software EngineeringComputer ScienceAWSGCP
$150k–$220k 9 days ago View →

Web Scraping Specialist

Wynd Labs · Remote
PythonJavaScriptBeautifulSoupScrapy
$70k–$140k 9 days ago View →

Staff Development Experience Engineer

Galaxydigitalservices · Remote
AWSCI/CDKubernetesGitHub
$112k–$188k 9 days ago View →

Senior Developer Experience Engineer

Galaxydigitalservices · Remote
PythonBashGoAWS
$98k–$162k 9 days ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.