Python Jobs in Crypto & Web3
Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.
Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.
Companies hiring Python talent
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Open Python roles
303 jobsDeFi Operations Specialist - Bullish
NewBullish · Remote
$100k–$145k
today
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Senior Risk Analyst
Coinbase · Remote
$167k–$197k
6 days ago
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Systematic Trader
Crypto · Hybrid
$38k–$62k
7 days ago
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Trading Support Analyst
Crypto · Hybrid
$75k–$125k
8 days ago
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Trading Support Analyst
Crypto · Hybrid
$75k–$125k
8 days ago
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Systematic Trader
Crypto · Hybrid
$38k–$62k
8 days ago
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Senior Data Scientist / Analyst, Finance
Polymarket · Remote
$200k–$300k
15 days ago
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Software Engineer - Solutions
Alchemy · Hybrid
$150k–$225k
19 days ago
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Senior DevOps Engineer (Trading Platform)
Crypto.com · Hybrid
$98k–$162k
22 days ago
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Senior Onchain Investigator
Coinbase · Remote
$52k–$88k
26 days ago
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Principal Security Architect (On-Chain & Digital Assets)
Btse · Remote
$128k–$212k
26 days ago
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Staff Platform Security Engineer
Phantom · Remote
$200k–$250k
27 days ago
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Team Lead Engineer - Crypto
Alpaca · Remote
$75k–$125k
28 days ago
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Binance Acceleration Program - Product Data Analyst
Binance · Remote
$90k–$150k
29 days ago
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People Intelligence Architect
Block · Remote
$108k–$203k
29 days ago
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Risk Manager, CDNA (Risk and Operations, Asia)
Crypto.com · Hybrid
$112k–$188k
1 month ago
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Threat Intelligence Platform Engineer
Coinbase · Remote
$82k–$138k
1 month ago
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Finance Systems Manager
Binance · Remote
$98k–$162k
1 month ago
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Staff Frontend Engineer / Senior Backend Engineer
Douro Labs / Zerion · Remote
$120k–$200k
1 month ago
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Threat Intelligence Platform Engineer
Coinbase · Remote
$145k–$170k
1 month ago
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Risk Manager, Quantitative
Crypto.com · Remote
$105k–$175k
1 month ago
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Risk Manager (Risk and Operations)
Crypto.com · Hybrid
$45k–$75k
1 month ago
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Member of Trading Operations
Anchorage · Remote
$45k–$75k
1 month ago
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Lead, Technical Compliance
Gemini · Remote
$140k–$200k
1 month ago
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Senior Staff Software Engineer, Finhub
Coinbase · Remote
$260k–$260k
1 month ago
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Python jobs by location
Frequently asked questions
Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.
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