Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

288open jobs
$112k–$180ktypical salary
148companies hiring
2added this week
100%remote

Open Python roles

288 jobs

Off-Cycle Fall 2026 Cybersecurity Internship

Galaxy Digital · Remote
PythonRustC++Solidity
$114k–$114k 3 days ago View →

Senior Data Scientist

Coinbase · Remote
SQLPythonData ScienceStatistical Analysis
$112k–$188k 4 days ago View →

Senior Data Scientist

Coinbase · Remote
SQLPythondata visualizationETL
$133k–$140k 7 days ago View →

Senior Backend Engineer / Senior QA Engineer / SDET

Zerion / Trust Wallet · Remote
GoDockerK8sPostgreSQL
$80k–$160k 7 days ago View →

Senior Software Engineer, Data Engineering Platform

Coinbase · Remote
PythonJavaSQLSnowflake
$186k–$219k 8 days ago View →

Core Developer - Node / Senior Site Reliability Engineer

Parity / SSV Labs · Remote
RustSubstratenetworkingpeer-to-peer
$100k–$160k 9 days ago View →

Compliance Senior Data Analyst

Crypto.com · Remote
SQLPythonAPIsdata analytics
$80k–$100k 11 days ago View →

Core Blockchain Engineer / Infrastructure / Systems Operations Engineer

Conduit / ZIGChain · Remote
GoPythonRustPostgres
$40k–$160k 13 days ago View →

Senior Data Scientist

Phantom · Remote
SQLRPython
$185k–$225k 14 days ago View →

IT & Platform Engineer

Centrifuge · Remote
GCPCloudflareGitHub ActionsDocker
$98k–$162k 23 days ago View →

Senior DevOps / Infrastructure Engineer

Category Labs · Remote
Linuxsystemdnetworkingshell
$180k–$250k 23 days ago View →

Fraud Strategy Manager

Stripe · Remote
AIdata analysisPythonR
$52k–$86k 1 month ago View →

SENIOR MARKETING ANALYST

Movavi · Remote
SQLPythonBI systemsstatistics
$75k–$120k 1 month ago View →

Backend Engineer (Data Platform), Software Engineer, Frontend / Full Stack, Senior Data Platform Engineer

Phantom, Provable · Remote
GoNode.jsTypeScriptKafka
$140k–$250k 1 month ago View →

Senior Full-Stack Software Developer

Luxoft · Remote
C#.NETWPFTypeScript
$50k–$80k 1 month ago View →

Senior Research Engineer - Safety Tooling and Data

Cohere · Remote
PythonPyTorchBigQuerySQL
$230k–$380k 1 month ago View →

Senior AI Engineer

Dvtrading · Remote
PythonKubernetesCI/CD
$200k–$300k 1 month ago View →

Senior Software Engineer, Developer Platform / SecOps Engineer

Offchain Labs / Lido · Remote
GoKubernetescryptographyPython
$100k–$160k 1 month ago View →

Lead, Advanced Analytics, Fraud and Safety Operations

Airbnb · Remote
data analyticsSQLPythonR
$164k–$191k 1 month ago View →

Senior Full-Stack Software Engineer, Social Commerce

Discord · Remote
PythonTypescriptReactElixir
$196k–$221k 1 month ago View →

Senior Machine Learning Operations Engineer

Mercury · Remote
PythonFastAPIFlaskSQL
$167k–$208k 1 month ago View →

Financial Crimes Compliance Modeling & Analytics Manager

Mercury · Remote
SQLPythonmachine learningdata analytics
$150k–$208k 1 month ago View →

Senior GRC Specialist

Cohere · Remote
compliancerisk managementAI governanceproject management
$140k–$220k 1 month ago View →

Applied AI Engineer, Learning Intelligence

Databricks · Remote
machine learningknowledge representationproduct engineeringPython
$111k–$191k 1 month ago View →

Data Scientist, Finance

Figma · Remote
SQLPythondata modelingdata analysis
$140k–$348k 1 month ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.