Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

254open jobs
$111k–$180ktypical salary
129companies hiring
10added this week
100%remote

Open Python roles

254 jobs

Senior Developer Experience Engineer

Galaxydigitalservices · Remote
PythonBashGoAWS
$98k–$162k 9 days ago View →

Machine Learning Engineer

Coinbase · Remote
machine learningpythonAIdeep learning
$120k–$200k 9 days ago View →

Security Engineer (Data Centers)

Galaxy Digital · Remote
PythonPowerShellBashSIEM
$130k–$180k 10 days ago View →

Senior Applied AI Engineer

Level Up Basketball · Remote
PythonTypeScriptGoAWS
$100k–$150k 10 days ago View →

Prediction Markets Trader

DRW · Remote
Pythonquantitative financestatisticsBayesian methods
$175k–$200k 10 days ago View →

Senior Software Development Engineer in Test (Automation, Python)

Binance · Remote
PythonBashUNIXLinux
$98k–$162k 10 days ago View →

Data Engineer

TradingView · Remote
PythonSQLAWSApache Airflow
$55k–$85k 11 days ago View →

Software Developer in Test (Python) – Senior

SOFTSWISS · Remote
PythonPyTestCI/CDAI testing
$115k–$196k 12 days ago View →

Senior DevOps Engineer

TradingView · Remote
KubernetesAWSTerraformAnsible
$80k–$130k 13 days ago View →

Scientific Data Engineer

Quantori · Remote
PythonRSQLAWS services
$81k–$138k 13 days ago View →

Database Engineer

Chess.com · Remote
MySQLPythonGoRedis
$81k–$138k 14 days ago View →

Senior Engineer, Load Integration & Model Development

Crusoe · Remote
Python
$175k–$210k 15 days ago View →

Experienced Quantitative Trader

Kronosresearch · Remote
quantitative researchrisk managementstatistical analysisPython
$105k–$112k 15 days ago View →

Risk Manager (Crypto Fund / DeFi & Quant Strategies)

EMCD · Remote
risk managementcryptoDeFiquantitative analysis
$92k–$155k 15 days ago View →

Hydrogen Fuel System Engineer

ZeroAvia · Remote
Mechanical Engineeringgas systemshydrogenhigh-pressure environments
$60k–$90k 15 days ago View →

Senior Machine Learning Engineer, CX Intelligence

Coinbase · Remote
PythonMachine LearningAINLP
$135k–$225k 16 days ago View →

Privacy Analyst

Coinbase · Remote
SQLPythondata analysisPostgres
$60k–$100k 16 days ago View →

Staff ML Risk Analyst

Coinbase · Remote
machine learningdata scienceSparkPython
$194k–$228k 16 days ago View →

Privacy Analyst

Coinbase · Remote
privacysecurityincident responsetechnology risk
$135k–$159k 17 days ago View →

IDM Analyst

N26 · Remote
advanced spreadsheetsSQLPython
$19k–$33k 18 days ago View →

Applied Science Manager / Lounge by Zalando (all genders)

Growth Content Creator · Remote
Machine LearningPythonOperations ResearchEconomics
$110k–$165k 19 days ago View →

Data Analyst

Alpaca · Remote
SQLPostgreSQLTrinoApache Iceberg
$68k–$112k 20 days ago View →

Quantitative Researcher - Prediction Markets, Quant Trading

Crypto.com · Remote
Pythondata engineeringquantitative modelingstatistics
$100k–$150k 21 days ago View →

Senior Solutions Architect, Banking and Capital Markets

Chainlink Labs · Remote
BlockchainDeFiMarketsPython
$125k–$273k 21 days ago View →

Blockchain Security Engineer - (Solidity / Rust / Golang)

CertiK · Remote
SolidityRustGolangPython
$102k–$180k 21 days ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.