Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

303open jobs
$108k–$175ktypical salary
147companies hiring
2added this week
93%remote

Open Python roles

303 jobs

Senior Platform Engineer

ZetaChain · Hybrid
GoPythonBashTerraform
$190k–$225k 1 month ago View →

Off-Cycle Fall 2026 Cybersecurity Internship

Galaxy Digital · Remote
Direct applyPythonRustC++Solidity
$114k–$114k 1 month ago View →

Senior Data Scientist

Coinbase · Remote
Direct applySQLPythondata visualizationETL
$133k–$140k 1 month ago View →

Senior Backend Engineer / Senior QA Engineer / SDET

Zerion / Trust Wallet · Remote
Direct applyGoDockerK8sPostgreSQL
$80k–$160k 1 month ago View →

Senior Software Engineer, Data Engineering Platform

Coinbase · Remote
PythonJavaSQLSnowflake
$186k–$219k 1 month ago View →

Application Support Engineer (US)

Crypto · Hybrid
SQLAPIswebhooksdata feeds
$75k–$125k 1 month ago View →

Compliance Senior Data Analyst

Crypto.com · Hybrid
SQLPythonAPIsdata analysis
$82k–$138k 1 month ago View →

Core Developer - Node / Senior Site Reliability Engineer

Parity / SSV Labs · Remote
Direct applyRustSubstratenetworkingpeer-to-peer
$100k–$160k 1 month ago View →

Senior DevOps / Infrastructure Engineer

Category Labs · Hybrid
AI-assisted engineeringSSHBlockchainMCP servers
$180k–$250k 1 month ago View →

Compliance Data Analyst

Crypto.com · Hybrid
SQLPythonAPIsJira
$68k–$112k 1 month ago View →

Compliance Senior Data Analyst

Crypto.com · Remote
SQLPythonAPIsdata analytics
$80k–$100k 1 month ago View →

Core Blockchain Engineer / Infrastructure / Systems Operations Engineer

Conduit / ZIGChain · Remote
Direct applyGoPythonRustPostgres
$40k–$160k 1 month ago View →

Senior Data Scientist

Phantom · Remote
SQLRPython
$185k–$225k 2 months ago View →

IT & Platform Engineer

Centrifuge · Remote
GCPCloudflareGitHub ActionsDocker
$98k–$162k 2 months ago View →

Senior DevOps / Infrastructure Engineer

Category Labs · Remote
Linuxsystemdnetworkingshell
$180k–$250k 2 months ago View →

Fraud Strategy Manager

Stripe · Remote
AIdata analysisPythonR
$52k–$86k 3 months ago View →

SENIOR MARKETING ANALYST

Movavi · Remote
SQLPythonBI systemsstatistics
$75k–$120k 3 months ago View →

Backend Engineer (Data Platform), Software Engineer, Frontend / Full Stack, Senior Data Platform Engineer

Phantom, Provable · Remote
GoNode.jsTypeScriptKafka
$140k–$250k 3 months ago View →

Senior Full-Stack Software Developer

Luxoft · Remote
C#.NETWPFTypeScript
$50k–$80k 3 months ago View →

Senior Research Engineer - Safety Tooling and Data

Cohere · Remote
PythonPyTorchBigQuerySQL
$230k–$380k 3 months ago View →

Senior AI Engineer

Dvtrading · Remote
Direct applyPythonKubernetesCI/CD
$200k–$300k 3 months ago View →

Senior Software Engineer, Developer Platform / SecOps Engineer

Offchain Labs / Lido · Remote
GoKubernetescryptographyPython
$100k–$160k 3 months ago View →

Lead, Advanced Analytics, Fraud and Safety Operations

Airbnb · Remote
Direct applydata analyticsSQLPythonR
$164k–$191k 3 months ago View →

Senior Full-Stack Software Engineer, Social Commerce

Discord · Remote
PythonTypescriptReactElixir
$196k–$221k 3 months ago View →

Senior Machine Learning Operations Engineer

Mercury · Remote
PythonFastAPIFlaskSQL
$167k–$208k 3 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.