Python Jobs in Crypto & Web3
Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.
Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.
Companies hiring Python talent
Top skills
Open Python roles
303 jobsSecurity Engineer (Data Centers) / Engineering Manager
Galaxy / Parity · Remote
$120k–$147k
4 months ago
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Senior Data Scientist (f/m/d)
adjoe · Remote
$90k–$135k
4 months ago
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Application Support Specialist
Full · Remote
$18k–$30k
4 months ago
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Senior Full Stack Engineer
HumanSignal · Remote
$115k–$196k
4 months ago
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Quant Researcher
Crypto.com · Remote
$100k–$230k
4 months ago
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Risk Manager
Crypto.com · Remote
$100k–$200k
4 months ago
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Senior Pre-Sales Engineer
Incode · Remote
$112k–$188k
4 months ago
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Head of Data Science - Generative AI
N26 · Remote
$55k–$88k
4 months ago
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Senior Data Scientist, Rides Safety
Bolt · Remote
$36k–$59k
4 months ago
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Senior Backend Engineer
Stellar Development Foundation · Hybrid
$185k–$275k
4 months ago
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Senior Security Engineer
NEAR Foundation · Remote
$130k–$180k
4 months ago
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Senior Frontend Engineer
HumanSignal · Remote
$115k–$196k
4 months ago
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Senior Quality Assurance Automation Engineer
Crypto · Hybrid
$75k–$125k
4 months ago
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Data Analytics AI Engineer
Fireblocks · Remote
$156k–$204k
4 months ago
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Machine Learning Engineer
Checkr · Remote
$100k–$150k
4 months ago
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Senior Quality Assurance Engineer (Crypto.com APP)
Crypto · Hybrid
$82k–$138k
4 months ago
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Senior Principal Applied Scientist - ZMS (all genders)
Growth Content Creator · Remote
$140k–$210k
4 months ago
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Security Response Engineer, Incident Response
Chainlink Labs · Remote
$154k–$360k
4 months ago
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AI/ML Engineer (all genders)
sunday · Remote
$65k–$95k
4 months ago
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Product Analyst
Aviasales · Remote
$92k–$150k
4 months ago
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Quantitative Trader (Associate/VP) - Onchain Trading
Galaxy Digital · Remote
$150k–$200k
4 months ago
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VP, Protocol Engineer (Validators)
Galaxydigitalservices · Remote
$68k–$112k
4 months ago
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Senior LLM Systems Engineer
Risk Labs · Remote
$100k–$200k
4 months ago
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Senior Blockchain/Web3 Engineer
Rather Labs · Remote
$180k–$180k
4 months ago
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Senior Backend Engineer
HumanSignal · Remote
$115k–$196k
4 months ago
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Python jobs by location
Frequently asked questions
Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.
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