Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

303open jobs
$108k–$175ktypical salary
147companies hiring
1added this week
93%remote

Open Python roles

303 jobs

Experienced Quantitative Trader

Kronosresearch · Remote
Direct applyquantitative researchrisk managementstatistical analysisPython
$105k–$112k 3 months ago View →

Risk Manager (Crypto Fund / DeFi & Quant Strategies)

EMCD · Remote
Direct applyrisk managementcryptoDeFiquantitative analysis
$92k–$155k 3 months ago View →

Hydrogen Fuel System Engineer

ZeroAvia · Remote
Mechanical Engineeringgas systemshydrogenhigh-pressure environments
$60k–$90k 3 months ago View →

Senior Machine Learning Engineer, CX Intelligence

Coinbase · Remote
Direct applyPythonMachine LearningAINLP
$135k–$225k 3 months ago View →

Privacy Analyst

Coinbase · Remote
Direct applySQLPythondata analysisPostgres
$60k–$100k 3 months ago View →

Staff ML Risk Analyst

Coinbase · Remote
Direct applymachine learningdata scienceSparkPython
$194k–$228k 3 months ago View →

Privacy Analyst

Coinbase · Remote
Direct applyprivacysecurityincident responsetechnology risk
$135k–$159k 4 months ago View →

IDM Analyst

N26 · Remote
advanced spreadsheetsSQLPython
$19k–$33k 4 months ago View →

Applied Science Manager / Lounge by Zalando (all genders)

Growth Content Creator · Remote
Direct applyMachine LearningPythonOperations ResearchEconomics
$110k–$165k 4 months ago View →

Data Analyst

Alpaca · Remote
SQLPostgreSQLTrinoApache Iceberg
$68k–$112k 4 months ago View →

Quantitative Researcher - Prediction Markets, Quant Trading

Crypto.com · Remote
Pythondata engineeringquantitative modelingstatistics
$100k–$150k 4 months ago View →

Senior Solutions Architect, Banking and Capital Markets

Chainlink Labs · Remote
BlockchainDeFiMarketsPython
$125k–$273k 4 months ago View →

Blockchain Security Engineer - (Solidity / Rust / Golang)

CertiK · Remote
SolidityRustGolangPython
$102k–$180k 4 months ago View →

Senior Compliance Tech Analyst, Platform (Compliance Automation)

Coinbase · Remote
Direct applySQLETLELTPython
$167k–$197k 4 months ago View →

Staff Machine Learning Engineer(Platform - Identity)

Coinbase · Remote
Direct applyMachine LearningPythonTensorFlowPyTorch
$150k–$250k 4 months ago View →

FP&A Analyst

Coinbase · Remote
Direct applyfinancial analysisforecastingvariance analysisSQL
$95k–$112k 4 months ago View →

Staff Machine Learning Engineer (Platform - Identity)

Coinbase · Remote
Direct applyPythonTensorFlowPyTorchML systems
$218k–$257k 4 months ago View →

Binance Accelerator Program - Fullstack Developer (Internal Applications)

Binance · Remote
TypeScriptReactNext.jsNode.js
$75k–$125k 4 months ago View →

Senior Machine Learning Engineer

Bluesky · Remote
PythonPyTorch
$221k–$405k 4 months ago View →

Senior Site Reliability Engineer, Workforce Identity

Coinbase · Remote
Direct applySite Reliability EngineeringIdentity and Access ManagementDevOpsCI/CD
$112k–$188k 4 months ago View →

Senior Site Reliability Engineer, Core AI Infrastructure

Coinbase · Remote
Direct applyAWSTerraformAnsibleChef
$112k–$188k 4 months ago View →

Data Analyst

SBI Investment · Remote
Direct applySQLdata visualizationTableauPower BI
$80k–$96k 4 months ago View →

Staff Software Engineer, EAA CX

Coinbase · Remote
Direct applybackend service designAPI developmentmicroservices architecturescloud-native infrastructure
$218k–$257k 4 months ago View →

Senior Staff Software Engineer, Payments

Coinbase · Remote
Direct applyPythonGoJava
$254k–$299k 4 months ago View →

Staff ML Risk Analytics

Coinbase · Remote
Direct applymachine learningdata scienceSparkPython
$98k–$162k 4 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.