Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

288open jobs
$112k–$180ktypical salary
148companies hiring
2added this week
100%remote

Open Python roles

288 jobs

Machine Learning Data Analyst

Incode · Remote
Data QualityPythonSQLAutomated Data Pipelines
$68k–$112k 3 months ago View →

Data Analyst, Risk

Binance · Remote
PythonSQLTableauPower BI
$88k–$198k 3 months ago View →

Senior Machine Learning Engineer (Nova)

Iterable · Remote
PythonTypeScriptMachine LearningLLM
$140k–$200k 3 months ago View →

Senior DevOps Engineer

BITFIT LABS PTE LTD · Remote
AWSTerraformDockerKubernetes
$150k–$180k 3 months ago View →

Derivatives Engineer

Galaxy Digital · Remote
PythonGoJavaKafka
$175k–$220k 3 months ago View →

Blockchain Developer (DeFi and Cryptography)

Signature IT World Inc · Remote
SolidityRustJavaScriptTypeScript
$110k–$140k 3 months ago View →

Senior Security Engineer - Automation

MoonPay · Remote
GoPythonNode.jsSAST
$210k–$221k 3 months ago View →

Quantitative Analyst, Derivatives & Financing

Anchorage · Remote
quantitative analysisfinancial modelingPythonrisk management
$98k–$162k 3 months ago View →

Senior Site Reliability Engineer

CaptivateIQ · Remote
TerraformAWSECSBash
$140k–$200k 4 months ago View →

Senior Automation QA Engineer (Python)

Jaxel · Remote
PythonREST APIsSQLjMeter
$115k–$196k 4 months ago View →

Smart Contract QA Engineer

Coinmarketcap · Remote
SolidityJavaScriptTypeScriptPython
$90k–$150k 4 months ago View →

Product Engineer

Sherlock · Remote
PythonNext.jsTypeScriptLLMs
$80k–$160k 4 months ago View →

Senior Backend Engineer: Attribute Enrichment (Remote)

Constructor · Remote
PythonAWSJenkinsGitHub Actions
$115k–$196k 4 months ago View →

Senior Data Scientist (Search)

Emerging Travel Group · Remote
PythonMLDLSQL
$115k–$196k 4 months ago View →

Market Risk Analyst

Alpaca · Remote
PythonSQLR
$52k–$88k 4 months ago View →

Senior AML Modeling Engineer (Payments & Crypto)

Coins.ph · Remote
PythonSQLmachine learningAML modeling
$136k–$230k 4 months ago View →

Data Scientist

Deel · Remote
PythonSQLdata sciencemachine learning
$81k–$138k 4 months ago View →

Payments Risk Analyst II

Coinbase · Remote
data analysisSQLMySQLfraud detection
$68k–$112k 4 months ago View →

Junior Derivatives Trader

Anchorage · Remote
derivativestradingrisk managementquantitative analysis
$120k–$200k 4 months ago View →

Payments Risk Analyst II

Coinbase · Remote
SQLMySQLdata analysisdata visualization
$102k–$110k 4 months ago View →

Analyst (FP&A)

Eqvilent · Remote
PythonMS Officeworkflow automation platforms
$63k–$109k 4 months ago View →

Software Architect

Manychat · Remote
Pythonmicroservicesdistributed architecturesCI/CD
$88k–$130k 4 months ago View →

Senior ML Engineer

Pravo Tech · Remote
PythonC++JavaScala
$115k–$196k 4 months ago View →

Product Operations Manager

Confirmo · Remote
AIno-code automationZapierPython
$95k–$200k 4 months ago View →

Analytics Engineer

Coinbase · Remote
SQLPythondata modelingdbt
$82k–$138k 4 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.