Python Jobs in Crypto & Web3
Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.
Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.
Companies hiring Python talent
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Open Python roles
254 jobsSenior Compliance Tech Analyst, Platform (Compliance Automation)
Coinbase · Remote
$167k–$197k
21 days ago
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Staff Machine Learning Engineer(Platform - Identity)
Coinbase · Remote
$150k–$250k
21 days ago
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FP&A Analyst
Coinbase · Remote
$95k–$112k
22 days ago
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Staff Machine Learning Engineer (Platform - Identity)
Coinbase · Remote
$218k–$257k
22 days ago
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Binance Accelerator Program - Fullstack Developer (Internal Applications)
Binance · Remote
$75k–$125k
22 days ago
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Senior Machine Learning Engineer
Bluesky · Remote
$221k–$405k
23 days ago
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Senior Site Reliability Engineer, Workforce Identity
Coinbase · Remote
$112k–$188k
23 days ago
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Senior Site Reliability Engineer, Core AI Infrastructure
Coinbase · Remote
$112k–$188k
23 days ago
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Data Analyst
SBI Investment · Remote
$80k–$96k
24 days ago
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Staff Software Engineer, EAA CX
Coinbase · Remote
$218k–$257k
24 days ago
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Senior Staff Software Engineer, Payments
Coinbase · Remote
$254k–$299k
24 days ago
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Staff ML Risk Analytics
Coinbase · Remote
$98k–$162k
24 days ago
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Security Engineer (Data Centers) / Engineering Manager
Galaxy / Parity · Remote
$120k–$147k
24 days ago
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Senior Data Scientist (f/m/d)
adjoe · Remote
$90k–$135k
25 days ago
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Application Support Specialist
Full · Remote
$18k–$30k
26 days ago
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Senior Full Stack Engineer
HumanSignal · Remote
$115k–$196k
27 days ago
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Quant Researcher
Crypto.com · Remote
$100k–$230k
27 days ago
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Risk Manager
Crypto.com · Remote
$100k–$200k
27 days ago
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Senior Pre-Sales Engineer
Incode · Remote
$112k–$188k
27 days ago
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Head of Data Science - Generative AI
N26 · Remote
$55k–$88k
29 days ago
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Senior Data Scientist, Rides Safety
Bolt · Remote
$36k–$59k
1 month ago
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Senior Security Engineer
NEAR Foundation · Remote
$130k–$180k
1 month ago
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Senior Frontend Engineer
HumanSignal · Remote
$115k–$196k
1 month ago
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Data Analytics AI Engineer
Fireblocks · Remote
$156k–$204k
1 month ago
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Machine Learning Engineer
Checkr · Remote
$100k–$150k
1 month ago
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Python jobs by location
Frequently asked questions
Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.
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