Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

288open jobs
$112k–$180ktypical salary
148companies hiring
2added this week
100%remote

Open Python roles

288 jobs

Credit Risk Analyst

Gauntlet · Remote
credit riskstructured financeasset-backed lendingPython
$160k–$195k 2 months ago View →

Platform Engineer - (Site Reliability Engineering)

Bitso · Remote
KubernetesCI/CDDevOpsPython
$112k–$188k 2 months ago View →

Application Support Engineer

Crypto.com · Remote
LinuxBashPythonSQL
$70k–$110k 2 months ago View →

Exchange Operations Automation Engineer

Crypto.com · Remote
PythonAirflowREST APILinux
$100k–$130k 2 months ago View →

Senior Agentic AI Engineer

Eigen Labs · Remote
GoPythonRustTypeScript
$187k–$253k 2 months ago View →

Data Engineer

Wynd Labs · Remote
SQLRedshiftSnowflakeApache Airflow
$100k–$140k 2 months ago View →

Technical Chief of Staff

Wynd Labs · Remote
Software EngineeringComputer ScienceAWSGCP
$150k–$220k 2 months ago View →

Web Scraping Specialist

Wynd Labs · Remote
PythonJavaScriptBeautifulSoupScrapy
$70k–$140k 2 months ago View →

Staff Development Experience Engineer

Galaxydigitalservices · Remote
AWSCI/CDKubernetesGitHub
$112k–$188k 2 months ago View →

Senior Developer Experience Engineer

Galaxydigitalservices · Remote
PythonBashGoAWS
$98k–$162k 2 months ago View →

Machine Learning Engineer

Coinbase · Remote
machine learningpythonAIdeep learning
$120k–$200k 2 months ago View →

Security Engineer (Data Centers)

Galaxy Digital · Remote
PythonPowerShellBashSIEM
$130k–$180k 2 months ago View →

Senior Applied AI Engineer

Level Up Basketball · Remote
PythonTypeScriptGoAWS
$100k–$150k 2 months ago View →

Prediction Markets Trader

DRW · Remote
Pythonquantitative financestatisticsBayesian methods
$175k–$200k 2 months ago View →

Senior Software Development Engineer in Test (Automation, Python)

Binance · Remote
PythonBashUNIXLinux
$98k–$162k 2 months ago View →

Data Engineer

TradingView · Remote
PythonSQLAWSApache Airflow
$55k–$85k 2 months ago View →

Software Developer in Test (Python) – Senior

SOFTSWISS · Remote
PythonPyTestCI/CDAI testing
$115k–$196k 2 months ago View →

Senior DevOps Engineer

TradingView · Remote
KubernetesAWSTerraformAnsible
$80k–$130k 2 months ago View →

Scientific Data Engineer

Quantori · Remote
PythonRSQLAWS services
$81k–$138k 2 months ago View →

Database Engineer

Chess.com · Remote
MySQLPythonGoRedis
$81k–$138k 2 months ago View →

Senior Engineer, Load Integration & Model Development

Crusoe · Remote
Python
$175k–$210k 2 months ago View →

Experienced Quantitative Trader

Kronosresearch · Remote
quantitative researchrisk managementstatistical analysisPython
$105k–$112k 2 months ago View →

Risk Manager (Crypto Fund / DeFi & Quant Strategies)

EMCD · Remote
risk managementcryptoDeFiquantitative analysis
$92k–$155k 2 months ago View →

Hydrogen Fuel System Engineer

ZeroAvia · Remote
Mechanical Engineeringgas systemshydrogenhigh-pressure environments
$60k–$90k 2 months ago View →

Senior Machine Learning Engineer, CX Intelligence

Coinbase · Remote
PythonMachine LearningAINLP
$135k–$225k 2 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.