Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

254open jobs
$111k–$180ktypical salary
129companies hiring
10added this week
100%remote

Open Python roles

254 jobs

Senior Compliance Tech Analyst, Platform (Compliance Automation)

Coinbase · Remote
SQLETLELTPython
$167k–$197k 21 days ago View →

Staff Machine Learning Engineer(Platform - Identity)

Coinbase · Remote
Machine LearningPythonTensorFlowPyTorch
$150k–$250k 21 days ago View →

FP&A Analyst

Coinbase · Remote
financial analysisforecastingvariance analysisSQL
$95k–$112k 22 days ago View →

Staff Machine Learning Engineer (Platform - Identity)

Coinbase · Remote
PythonTensorFlowPyTorchML systems
$218k–$257k 22 days ago View →

Binance Accelerator Program - Fullstack Developer (Internal Applications)

Binance · Remote
TypeScriptReactNext.jsNode.js
$75k–$125k 22 days ago View →

Senior Machine Learning Engineer

Bluesky · Remote
PythonPyTorch
$221k–$405k 23 days ago View →

Senior Site Reliability Engineer, Workforce Identity

Coinbase · Remote
Site Reliability EngineeringIdentity and Access ManagementDevOpsCI/CD
$112k–$188k 23 days ago View →

Senior Site Reliability Engineer, Core AI Infrastructure

Coinbase · Remote
AWSTerraformAnsibleChef
$112k–$188k 23 days ago View →

Data Analyst

SBI Investment · Remote
SQLdata visualizationTableauPower BI
$80k–$96k 24 days ago View →

Staff Software Engineer, EAA CX

Coinbase · Remote
backend service designAPI developmentmicroservices architecturescloud-native infrastructure
$218k–$257k 24 days ago View →

Senior Staff Software Engineer, Payments

Coinbase · Remote
PythonGoJava
$254k–$299k 24 days ago View →

Staff ML Risk Analytics

Coinbase · Remote
machine learningdata scienceSparkPython
$98k–$162k 24 days ago View →

Security Engineer (Data Centers) / Engineering Manager

Galaxy / Parity · Remote
PythonPowerShellBashSplunk
$120k–$147k 24 days ago View →

Senior Data Scientist (f/m/d)

adjoe · Remote
PythonPyTorchTensorFlowTrino
$90k–$135k 25 days ago View →

Application Support Specialist

Full · Remote
Atlassian (Jira, Confluence)Microsoft 365TrelicaGrafana
$18k–$30k 26 days ago View →

Senior Full Stack Engineer

HumanSignal · Remote
PythonDjangoReactTypeScript
$115k–$196k 27 days ago View →

Quant Researcher

Crypto.com · Remote
PythonSQLnoSQLdata structures
$100k–$230k 27 days ago View →

Risk Manager

Crypto.com · Remote
PythonSQL
$100k–$200k 27 days ago View →

Senior Pre-Sales Engineer

Incode · Remote
AndroidSwiftPythonKotlin
$112k–$188k 27 days ago View →

Head of Data Science - Generative AI

N26 · Remote
Generative AIMachine LearningPythonMLOps
$55k–$88k 29 days ago View →

Senior Data Scientist, Rides Safety

Bolt · Remote
machine learningPythonSQL
$36k–$59k 1 month ago View →

Senior Security Engineer

NEAR Foundation · Remote
IAMendpointcloudPython
$130k–$180k 1 month ago View →

Senior Frontend Engineer

HumanSignal · Remote
PythonDjangoJavaScriptTypeScript
$115k–$196k 1 month ago View →

Data Analytics AI Engineer

Fireblocks · Remote
AI/MLSQLPythonLLMs
$156k–$204k 1 month ago View →

Machine Learning Engineer

Checkr · Remote
PythonML systemsLLM APIsCI/CD
$100k–$150k 1 month ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.