Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

288open jobs
$112k–$180ktypical salary
148companies hiring
2added this week
100%remote

Open Python roles

288 jobs

Privacy Analyst

Coinbase · Remote
SQLPythondata analysisPostgres
$60k–$100k 2 months ago View →

Staff ML Risk Analyst

Coinbase · Remote
machine learningdata scienceSparkPython
$194k–$228k 2 months ago View →

Privacy Analyst

Coinbase · Remote
privacysecurityincident responsetechnology risk
$135k–$159k 2 months ago View →

IDM Analyst

N26 · Remote
advanced spreadsheetsSQLPython
$19k–$33k 2 months ago View →

Applied Science Manager / Lounge by Zalando (all genders)

Growth Content Creator · Remote
Machine LearningPythonOperations ResearchEconomics
$110k–$165k 2 months ago View →

Data Analyst

Alpaca · Remote
SQLPostgreSQLTrinoApache Iceberg
$68k–$112k 2 months ago View →

Quantitative Researcher - Prediction Markets, Quant Trading

Crypto.com · Remote
Pythondata engineeringquantitative modelingstatistics
$100k–$150k 2 months ago View →

Senior Solutions Architect, Banking and Capital Markets

Chainlink Labs · Remote
BlockchainDeFiMarketsPython
$125k–$273k 2 months ago View →

Blockchain Security Engineer - (Solidity / Rust / Golang)

CertiK · Remote
SolidityRustGolangPython
$102k–$180k 2 months ago View →

Senior Compliance Tech Analyst, Platform (Compliance Automation)

Coinbase · Remote
SQLETLELTPython
$167k–$197k 2 months ago View →

Staff Machine Learning Engineer(Platform - Identity)

Coinbase · Remote
Machine LearningPythonTensorFlowPyTorch
$150k–$250k 2 months ago View →

FP&A Analyst

Coinbase · Remote
financial analysisforecastingvariance analysisSQL
$95k–$112k 2 months ago View →

Staff Machine Learning Engineer (Platform - Identity)

Coinbase · Remote
PythonTensorFlowPyTorchML systems
$218k–$257k 2 months ago View →

Binance Accelerator Program - Fullstack Developer (Internal Applications)

Binance · Remote
TypeScriptReactNext.jsNode.js
$75k–$125k 2 months ago View →

Senior Machine Learning Engineer

Bluesky · Remote
PythonPyTorch
$221k–$405k 2 months ago View →

Senior Site Reliability Engineer, Workforce Identity

Coinbase · Remote
Site Reliability EngineeringIdentity and Access ManagementDevOpsCI/CD
$112k–$188k 2 months ago View →

Senior Site Reliability Engineer, Core AI Infrastructure

Coinbase · Remote
AWSTerraformAnsibleChef
$112k–$188k 2 months ago View →

Data Analyst

SBI Investment · Remote
SQLdata visualizationTableauPower BI
$80k–$96k 2 months ago View →

Staff Software Engineer, EAA CX

Coinbase · Remote
backend service designAPI developmentmicroservices architecturescloud-native infrastructure
$218k–$257k 2 months ago View →

Senior Staff Software Engineer, Payments

Coinbase · Remote
PythonGoJava
$254k–$299k 2 months ago View →

Staff ML Risk Analytics

Coinbase · Remote
machine learningdata scienceSparkPython
$98k–$162k 2 months ago View →

Security Engineer (Data Centers) / Engineering Manager

Galaxy / Parity · Remote
PythonPowerShellBashSplunk
$120k–$147k 2 months ago View →

Senior Data Scientist (f/m/d)

adjoe · Remote
PythonPyTorchTensorFlowTrino
$90k–$135k 2 months ago View →

Application Support Specialist

Full · Remote
Atlassian (Jira, Confluence)Microsoft 365TrelicaGrafana
$18k–$30k 2 months ago View →

Senior Full Stack Engineer

HumanSignal · Remote
PythonDjangoReactTypeScript
$115k–$196k 2 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.