Python Jobs in Crypto & Web3
Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.
Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.
Companies hiring Python talent
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Open Python roles
254 jobsSenior Principal Applied Scientist - ZMS (all genders)
Growth Content Creator · Remote
$140k–$210k
1 month ago
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Security Response Engineer, Incident Response
Chainlink Labs · Remote
$154k–$360k
1 month ago
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AI/ML Engineer (all genders)
sunday · Remote
$65k–$95k
1 month ago
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Product Analyst
Aviasales · Remote
$92k–$150k
1 month ago
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Quantitative Trader (Associate/VP) - Onchain Trading
Galaxy Digital · Remote
$150k–$200k
1 month ago
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VP, Protocol Engineer (Validators)
Galaxydigitalservices · Remote
$68k–$112k
1 month ago
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Senior LLM Systems Engineer
Risk Labs · Remote
$100k–$200k
1 month ago
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Senior Blockchain/Web3 Engineer
Rather Labs · Remote
$180k–$180k
1 month ago
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Senior Backend Engineer
HumanSignal · Remote
$115k–$196k
1 month ago
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Senior Analytics Engineer
Alpaca · Remote
$117k–$127k
1 month ago
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Senior Business System Analyst
Symfa · Remote
$127k–$196k
1 month ago
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Vice President Security Engineering (Data Centers)
Galaxydigitalservices · Remote
$120k–$200k
1 month ago
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Site Reliability Engineer
Alpaca · Remote
$98k–$162k
1 month ago
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Senior Software Engineer - Core Trading
Alpaca · Remote
$98k–$162k
1 month ago
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Senior Security Engineer
Nearfoundation · Remote
$120k–$150k
1 month ago
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Senior C++ Developer
Movavi · Remote
$115k–$196k
1 month ago
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Senior Systems Reliability Engineer - IEX
IEX · Remote
$150k–$225k
1 month ago
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Counterparty Credit Risk Analyst
N26 · Remote
$34k–$56k
1 month ago
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Senior Backend Engineer
Zerion · Remote
$115k–$196k
1 month ago
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Junior Blockchain Accountant
General Tensor · Remote
$50k–$60k
1 month ago
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VP, Quantitative Developer - Risk Engineering
Galaxy Digital · Remote
$225k–$280k
1 month ago
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Privacy Automation Engineer
Binance · Remote
$68k–$112k
1 month ago
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Middle DevOps specialist
Asodesk · Remote
$38k–$38k
1 month ago
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Vice President Site Reliability Engineering (Data Centers)
Galaxydigitalservices · Remote
$120k–$200k
1 month ago
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Blockchain Security AI Application Support Engineer
Crypto · Remote
$75k–$125k
1 month ago
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Python jobs by location
Frequently asked questions
Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.
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