Python Jobs in Crypto & Web3
Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.
Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.
Companies hiring Python talent
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Open Python roles
255 jobsSenior DevOps Engineer
Risk Labs · Remote
$100k–$200k
2 months ago
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Senior Blockchain Engineer (Rust) & Senior Data Engineer
Trust Wallet · Remote
$90k–$140k
2 months ago
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Python Engineer
Checkr · Remote
$100k–$150k
2 months ago
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Senior Blockchain Engineer
JSoft Labs · Remote
$100k–$140k
2 months ago
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Senior/Staff Machine Learning Engineer
River · Remote
$150k–$250k
2 months ago
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Principal Security Engineer, Research & Engineering
Trail of Bits · Remote
$200k–$250k
2 months ago
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Software Engineer - Affirmative for People with Disabilities
Neon · Remote
$81k–$138k
2 months ago
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Technical Operations Analyst
Coins.ph · Remote
$120k–$220k
2 months ago
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Senior SRE (blockchain networks)
P2P.org · Remote
$138k–$220k
2 months ago
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AI Native Platform Architect
Okx · Remote
$180k–$219k
2 months ago
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Tokenization and Investment Operations Specialist
Centrifuge · Remote
$52k–$88k
2 months ago
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Data Governance and Management Lead
Anchorage · Remote
$135k–$225k
2 months ago
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Capital and Risk Analytics Lead
Anchorage Digital · Remote
$120k–$200k
2 months ago
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Backend Engineer: Ranking
Constructor · Remote
$81k–$138k
2 months ago
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Senior Risk Engineer
Luxoft · Remote
$115k–$196k
2 months ago
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Data Governance and Management Lead
Anchorage Digital · Remote
$117k–$218k
2 months ago
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Senior Backend Engineer (Python/Java)
BTSE · Remote
$135k–$225k
2 months ago
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Agentic AI Engineer
Eigen Labs · Remote
$187k–$253k
2 months ago
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Senior FullStack Developer
Palta · Remote
$115k–$196k
2 months ago
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AI Agent Platform Engineer
Binance · Remote
$180k–$219k
2 months ago
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Research Analyst
Tether Operations Limited · Remote
$140k–$230k
2 months ago
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DeFi Yield Strategist
Cannon Ventures · Remote
$95k–$145k
2 months ago
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Senior Software Engineer
Toku · Remote
$165k–$220k
2 months ago
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Senior Solutions Engineer (API, Python, Node.JS)
Binance · Remote
$112k–$188k
2 months ago
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Binance Accelerator Program - Data Scientist (LLM & Trading)
Binance · Remote
$112k–$188k
2 months ago
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Python jobs by location
Frequently asked questions
Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.
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