Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

303open jobs
$108k–$175ktypical salary
147companies hiring
1added this week
93%remote

Open Python roles

303 jobs

Senior Fraud Strategist

Gemini · Remote
SQLPythonLookerdata analysis
$116k–$155k 5 months ago View →

Senior Data Scientist - Risk

Shakepay · Remote
SQLPythonmachine learningdata analysis
$97k–$124k 5 months ago View →

High Potential Program - IT Support

Impossible Cloud · Remote
IT supportcloud computingAILinux
$88k–$155k 5 months ago View →

Operations Manager

Hivemind Capital Partners · Remote
trading operationsportfolio management systemsreconciliationdigital assets
$130k–$140k 5 months ago View →

Blockchain Developer

Swift · Remote
Direct applyblockchaindistributed ledger technologysmart contractsEthereum
$101k–$188k 5 months ago View →

DeFi Risk Engineer

ether.fi · Remote
PythonTypeScript
$130k–$150k 5 months ago View →

Senior Machine Learning Engineer: Search Quality

Constructor · Remote
PythonPyTorchSQLSpark
$115k–$196k 5 months ago View →

Business Intelligence / Data Scientist

Binance · Remote
MathematicsStatisticsActuarial SciencesComputer Science
$148k–$200k 5 months ago View →

Machine Learning Data Analyst

Incode · Remote
Data QualityPythonSQLAutomated Data Pipelines
$68k–$112k 5 months ago View →

Data Analyst, Risk

Binance · Remote
PythonSQLTableauPower BI
$88k–$198k 5 months ago View →

Senior Machine Learning Engineer (Nova)

Iterable · Remote
PythonTypeScriptMachine LearningLLM
$140k–$200k 5 months ago View →

Senior DevOps Engineer

BITFIT LABS PTE LTD · Remote
AWSTerraformDockerKubernetes
$150k–$180k 5 months ago View →

Derivatives Engineer

Galaxy Digital · Remote
Direct applyPythonGoJavaKafka
$175k–$220k 5 months ago View →

Blockchain Security AI Application Support Engineer

Crypto · Hybrid
AIBlockchainWeb3Rust
$75k–$125k 5 months ago View →

Blockchain Security AI Application Support Engineer

Crypto.com · Hybrid
AIBlockchainWeb3DApps
$75k–$125k 5 months ago View →

Blockchain Developer (DeFi and Cryptography)

Signature IT World Inc · Remote
SolidityRustJavaScriptTypeScript
$110k–$140k 5 months ago View →

Senior Security Engineer - Automation

MoonPay · Remote
GoPythonNode.jsSAST
$210k–$221k 5 months ago View →

Senior Java Developer (Trading Platform)

Crypto.com · Hybrid
JavaPythonReactAg-Grid
$82k–$138k 5 months ago View →

Application Support Engineer

Crypto · Hybrid
UNIXSQLBashPython
$75k–$125k 5 months ago View →

Quantitative Analyst, Derivatives & Financing

Anchorage · Remote
Direct applyquantitative analysisfinancial modelingPythonrisk management
$98k–$162k 5 months ago View →

Senior Site Reliability Engineer

CaptivateIQ · Remote
TerraformAWSECSBash
$140k–$200k 5 months ago View →

Senior Automation QA Engineer (Python)

Jaxel · Remote
PythonREST APIsSQLjMeter
$115k–$196k 5 months ago View →

Smart Contract QA Engineer

Coinmarketcap · Remote
SolidityJavaScriptTypeScriptPython
$90k–$150k 5 months ago View →

Product Engineer

Sherlock · Remote
Direct applyPythonNext.jsTypeScriptLLMs
$80k–$160k 5 months ago View →

Senior Backend Engineer: Attribute Enrichment (Remote)

Constructor · Remote
PythonAWSJenkinsGitHub Actions
$115k–$196k 5 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.