Python Jobs in Crypto & Web3
Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.
Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.
Companies hiring Python talent
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Open Python roles
255 jobsSenior DevOps Engineer
Risk Labs · Remote
$100k–$200k
2 months ago
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BI Senior Manager
Coins.ph · Remote
$130k–$233k
2 months ago
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Engineering Lead - Crypto and DeFi
Kast · Remote
$175k–$250k
2 months ago
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Technical Content Marketing Manager
Alpaca · Remote
$98k–$162k
2 months ago
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Senior Threat Researcher - Threatlabz
Zscaler · Remote
$120k–$240k
2 months ago
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Senior Analytics Engineer (Platform - Financial Analytics)
Coinbase · Remote
$112k–$188k
2 months ago
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Software Engineer, Trading Bot Developer
PumaPulse · Remote
$90k–$90k
2 months ago
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Senior Analytics Engineer (Platform - Financial Analytics)
Coinbase · Remote
$180k–$212k
2 months ago
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Multimodal Large Language Models AI Engineer
Headroom Inc. · Remote
$100k–$150k
2 months ago
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AI & Optimization Engineer
Tether Operations Limited · Remote
$150k–$200k
2 months ago
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Senior Analytics Engineer
Consensys · Remote
$100k–$140k
2 months ago
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Staff Data Engineer
Checkr · Remote
$140k–$200k
2 months ago
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Senior AI Translation Engineer (NLP)
Smartcat · Remote
$80k–$130k
2 months ago
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Engagement Manager
Tether Operations Limited · Remote
$60k–$200k
3 months ago
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Fireblocks Implementation Developer
PURVIEW · Remote
$140k–$201k
3 months ago
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Technical Project Manager QVAC
Tether Operations Limited · Remote
$150k–$200k
3 months ago
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Product Support Engineer III - DLP
Zscaler · Remote
$77k–$150k
3 months ago
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Technical Support Engineer
Zscaler · Remote
$70k–$155k
3 months ago
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Sr. Staff Technical Program Manager - Hosted Infrastructure Operations
Zscaler · Remote
$140k–$200k
3 months ago
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Staff Site Reliability Engineer-Federal, Security Clearance
Zscaler · Remote
$119k–$170k
3 months ago
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DeFi Risk Analyst
Morpho · Remote
$95k–$170k
3 months ago
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Data Scientist - Credit Risk
Divine · Remote
$135k–$237k
3 months ago
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Blockchain Developer
Harris Allied · Remote
$175k–$195k
3 months ago
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Senior Post Listing Account Manager
Binance · Remote
$76k–$220k
3 months ago
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Machine Learning Engineer Intern
Tether Operations Limited · Remote
$60k–$90k
3 months ago
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Python jobs by location
Frequently asked questions
Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.
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