Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

255open jobs
$110k–$180ktypical salary
130companies hiring
9added this week
100%remote

Open Python roles

255 jobs

Senior DevOps Engineer

Risk Labs · Remote
TerraformBashPythonGCP
$100k–$200k 2 months ago View →

BI Senior Manager

Coins.ph · Remote
TableauPower BILookerSQL
$130k–$233k 2 months ago View →

Engineering Lead - Crypto and DeFi

Kast · Remote
GoPythonNode.jsSolana
$175k–$250k 2 months ago View →

Technical Content Marketing Manager

Alpaca · Remote
PythonGitHub
$98k–$162k 2 months ago View →

Senior Threat Researcher - Threatlabz

Zscaler · Remote
PythonRubyGoShell
$120k–$240k 2 months ago View →

Senior Analytics Engineer (Platform - Financial Analytics)

Coinbase · Remote
SQLPythonAirflowLooker
$112k–$188k 2 months ago View →

Software Engineer, Trading Bot Developer

PumaPulse · Remote
Node.jsPythonReactNext.js
$90k–$90k 2 months ago View →

Senior Analytics Engineer (Platform - Financial Analytics)

Coinbase · Remote
SQLPythonLookerTableau
$180k–$212k 2 months ago View →

Multimodal Large Language Models AI Engineer

Headroom Inc. · Remote
PythonTensorFlowPyTorchGo
$100k–$150k 2 months ago View →

AI & Optimization Engineer

Tether Operations Limited · Remote
PythonPyTorchTensorFlowScikit-Learn
$150k–$200k 2 months ago View →

Senior Analytics Engineer

Consensys · Remote
SQLdbtBI toolsLooker
$100k–$140k 2 months ago View →

Staff Data Engineer

Checkr · Remote
PySparkPythonSQLKafka
$140k–$200k 2 months ago View →

Senior AI Translation Engineer (NLP)

Smartcat · Remote
PythonC#PyTorchTransformers
$80k–$130k 2 months ago View →

Engagement Manager

Tether Operations Limited · Remote
APIssystem integrationsPythonJavaScript
$60k–$200k 3 months ago View →

Fireblocks Implementation Developer

PURVIEW · Remote
JavaPythonNode.jsGo
$140k–$201k 3 months ago View →

Technical Project Manager QVAC

Tether Operations Limited · Remote
JavaScriptPythonJavaC#
$150k–$200k 3 months ago View →

Product Support Engineer III - DLP

Zscaler · Remote
DLP technologiesSymantec DLPMcAfee DLPForcepoint DLP
$77k–$150k 3 months ago View →

Technical Support Engineer

Zscaler · Remote
firewallspacket filteringHTTP/HTTPSIPv4
$70k–$155k 3 months ago View →

Sr. Staff Technical Program Manager - Hosted Infrastructure Operations

Zscaler · Remote
networkingcloud operationsinfrastructuredata center technologies
$140k–$200k 3 months ago View →

Staff Site Reliability Engineer-Federal, Security Clearance

Zscaler · Remote
AWSLinuxAnsibleTerraform
$119k–$170k 3 months ago View →

DeFi Risk Analyst

Morpho · Remote
SQLPythonR
$95k–$170k 3 months ago View →

Data Scientist - Credit Risk

Divine · Remote
PythonSQLGrafanaPrometheus
$135k–$237k 3 months ago View →

Blockchain Developer

Harris Allied · Remote
SolidityJavaTypescriptPython
$175k–$195k 3 months ago View →

Senior Post Listing Account Manager

Binance · Remote
Google suiteSQLPythonDune analytics
$76k–$220k 3 months ago View →

Machine Learning Engineer Intern

Tether Operations Limited · Remote
PythonPyTorchdeep learninggenerative modeling
$60k–$90k 3 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.