Python Jobs in Crypto & Web3

Python shows up across web3 in data analytics, on-chain research, trading and MEV bots, and tooling. Libraries like web3.py let engineers query nodes and decode events, while pandas and the broader data stack power dashboards, risk models, and protocol analytics that inform real decisions.

Employers hiring Python developers often want someone who can pull and clean on-chain data, build backtesting or monitoring pipelines, and prototype quickly. Roles range from quantitative research at trading desks to backend services and data engineering at protocols, where reliability and clear reproducible analysis matter as much as raw modeling skill.

303open jobs
$108k–$175ktypical salary
147companies hiring
1added this week
93%remote

Open Python roles

303 jobs

Senior Data Scientist (Search)

Emerging Travel Group · Remote
PythonMLDLSQL
$115k–$196k 5 months ago View →

Market Risk Analyst

Alpaca · Remote
PythonSQLR
$52k–$88k 5 months ago View →

Senior AML Modeling Engineer (Payments & Crypto)

Coins.ph · Remote
PythonSQLmachine learningAML modeling
$136k–$230k 5 months ago View →

Data Scientist

Deel · Remote
Direct applyPythonSQLdata sciencemachine learning
$81k–$138k 5 months ago View →

Full Stack Engineer, Blockchain

Fireblocks · Hybrid
GoPythonJavaScriptTypeScript
$82k–$138k 5 months ago View →

Payments Risk Analyst II

Coinbase · Remote
Direct applydata analysisSQLMySQLfraud detection
$68k–$112k 5 months ago View →

Junior Derivatives Trader

Anchorage · Remote
Direct applyderivativestradingrisk managementquantitative analysis
$120k–$200k 5 months ago View →

Payments Risk Analyst II

Coinbase · Remote
Direct applySQLMySQLdata analysisdata visualization
$102k–$110k 5 months ago View →

Analyst (FP&A)

Eqvilent · Remote
Direct applyPythonMS Officeworkflow automation platforms
$63k–$109k 5 months ago View →

Software Architect

Manychat · Remote
Pythonmicroservicesdistributed architecturesCI/CD
$88k–$130k 5 months ago View →

Senior ML Engineer

Pravo Tech · Remote
PythonC++JavaScala
$115k–$196k 5 months ago View →

Product Operations Manager

Confirmo · Remote
AIno-code automationZapierPython
$95k–$200k 5 months ago View →

Analytics Engineer

Coinbase · Remote
Direct applySQLPythondata modelingdbt
$82k–$138k 5 months ago View →

Senior Developer Relations and Community Manager - Brave Search API

Brave · Remote
PythonJavaScript
$98k–$162k 5 months ago View →

Technical Support Engineer (Blockchain & Backend Development)

Binance · Remote
JavaPythonRustSpring Boot
$98k–$162k 5 months ago View →

Smart Contract QA Engineer (Oracle)

CoinMarketCap · Remote
SolidityJavaScriptTypeScriptPython
$81k–$138k 5 months ago View →

Senior Site Reliability Engineer

Bloxstaking · Remote
Direct applyKubernetesArgoCDTerraformCrossplane
$82k–$112k 5 months ago View →

Principal AI Engineer

Figure · Remote
generative AILLMsmachine learningcloud platforms
$176k–$220k 5 months ago View →

Software Engineer I - AI and ML

Zinnia · Remote
PythonNumPyPandasFastAPI
$100k–$160k 5 months ago View →

Pioneer Talent Program - Product Manager, Trading Systems

Binance · Remote
MathematicsQuantitative FinanceFinancial EngineeringComputer Science
$112k–$188k 5 months ago View →

Trader

Wormhole Labs · Remote
crypto tradingmarket-makingliquidity provisioningPython
$40k–$120k 5 months ago View →

Project Coordinator - CEO Office (MLO)

Binance · Remote
project managementcompliancelegal supportbusiness analysis
$80k–$165k 5 months ago View →

Staff Economist, Marketplace Experimentation

Bolt · Remote
econometricscausal inferencePythondata science
$90k–$135k 5 months ago View →

Principal AI Engineer

Figure · Remote
PythonSQLMLAI
$176k–$264k 5 months ago View →

Pioneer Talent Program - Software Engineer - Blockchain Security

Binance · Remote
JavaPythonGo
$98k–$162k 5 months ago View →

Frequently asked questions

Is Python used for smart contract development?
Rarely for production contracts, though Vyper borrows Python-like syntax. Python's strength in web3 is data, analytics, automation, and bots rather than on-chain logic.
What library do I use to read blockchain data in Python?
Web3.py is the standard for interacting with Ethereum nodes, decoding events, and sending transactions. Many analytics roles also rely on indexed datasets and SQL.
Can Python skills land a quant or MEV role?
Yes. Trading desks and MEV teams use Python heavily for research and prototyping, often alongside Rust or C++ for latency-critical execution.